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Ingredient science

Bacopa monnieri: Human Cognition Research

A closer look at randomized trials and systematic reviews of Bacopa monnieri in cognitive research.

What is Bacopa monnieri?

Bacopa monnieri is one of the ingredients currently listed in NeuroPrime vendor materials. Ingredient identity alone does not tell us the exact extract, concentration or dose used in the finished product.

What researchers study

Research involving Bacopa monnieri spans laboratory, animal and/or human studies depending on the ingredient. The most useful evidence for a buyer is well-designed human research using a clearly defined preparation and dose.

A 2012 systematic review identified six randomized controlled trials, all lasting 12 weeks, and found some evidence of improvement in memory free recall with the studied Bacopa extracts. The review also emphasized that evidence for other cognitive domains was limited. A later 2013 meta-analysis also reported potential cognitive effects but called for stronger comparative research.

Why this does not prove NeuroPrime works

NeuroPrime is a multi-ingredient finished product. A study of one ingredient cannot be assumed to predict the effect of the full formula. The supplied materials also do not include a verified Supplement Facts panel, so a dose match cannot be established.

Safety and interaction questions

Botanical and algae-derived supplements can have side effects, allergens, contamination concerns or medication interactions. Review the current label and discuss concerns with a qualified healthcare professional.

How to evaluate a study

  • Was it conducted in humans?
  • Was it randomized and placebo controlled?
  • What extract and dose were used?
  • How long did the study last?
  • Was the outcome clinically meaningful?
  • Can the study conditions be compared with the finished supplement?

References and further reading

  1. U.S. FDA — FDA 101: Dietary Supplements
  2. Pase MP, et al. Systematic review of randomized controlled trials of Bacopa monnieri
  3. Pase MP, et al. Meta-analysis of randomized controlled trials on cognitive effects of Bacopa monnieri extract
  4. PubMed search: Bacopa monnieri human research

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